Anthropoid Evolution
Genetics
Quantitative Morphology
Bioinformatics
Research Team
Publications
Useful Links
Research Team

Principal investigators (PIs)


James Cheverud
cheverud(at)pcg.wustl.edu
Professor of Anatomy and Anthropology, WUSTL
Joan Richtsmeier
jta10(at)psu.edu
Professor of Biological Anthropology, PSU          
Jeff Rogers
jrogers(at)darwin.sfbr.org
Scientist Department of Genetics, SFBR
Alan Walker
axw8(at)psu.edu
Evan Pugh Professor in Biological Anthropology and Biology, PSU
Kenneth Weiss
KenWeiss(at)psu.edu
Evan Pugh Professor in Biological Anthropology and Genetics, PSU
Others Involved
Anne BuchananAnneBuchanan(at)psu.edu
Senior research scientist, PSU
Heather Lawsonhal130(at)psu.edu
Ph.D. Student, PSU
Brenda Frazierbcf134(at)psu.edu
Ph.D. Student, PSU
Charles Rosemancroseman(at)uiuc.edu
Assistant Professor, Univeristy of Illiois
Charles Hildebolt
Associate Professor of Radiology, WUSTL
Katherine Willmorekew20(at)psu.edu
Postdoc, PSU
Cheryl Hillcah277(at)psu.edu
Ph.D. Student, PSU
Peng Yanpzy1(at)psu.edu
Research Associate, PSU
Nina Jablonskingj2(at)psu.edu
Head, Department of Anthropology, PSU

Research Institutions

Penn State University

Southwest Foundation

Washington University in St. Louis

Publications

Willmore KE, Lawson HA, Roseman CC, Rogers J, Cox LA, Mahaney MC, Cheverud JM, and Richtsmeier JT. 2008.  Comparison of phenotypic and genetic integration between mouse and baboon.   American Journal of Physical Anthropology. 135(S46): 224.

In this study we use mouse and baboon mandibular data to determine if, and to what degree, morphological homology corresponds with genetic homology. Understanding the association between genetic and morphological homology will help us to determine how the genotype-to-phenotype map corresponds between species… [FULL ABSTRACT]

Percival C, Hill CA, Sun M, Wang Y, Jabs EW, and Richtsmeier JT. 2008.  Phenotypic variation within and between 'genetically homogeneous' mouse litters.   American Journal of Physical Anthropology. 135(S46): 170.

The human occipital bone is often viewed as a single osseous element, though it is a fusion of five major skeletal elements. The basioccipital, L and R exoccipitals, and supraoccipital are all formed endochondrally, while the interparietal forms intramembranously...[FULL ABSTRACT][POSTER]

Lawson HA, Lesk AM, Miller W, and Weiss KM. 2006.  A comparative genomics approach to primate craniofacial evolution.   The American Journal of Physical Anthropology. 129(S42):119.

Changes in primate craniofacial size and shape are well documented, providing much information on both the tempo and the mode of hominid evolution. However, until the fundamental molecular factors underlying these changes are understood, knowledge of hominid skull evolution is limited… [FULL ABSTRACT]

Hill C.   Three-dimensional analysis of temporal bone pneumatization patterns in olive baboons.   The American Journal of Physical Anthropology 132(S44):129.in press

While most cercopithecines lack paranasal sinuses, extensive pneumatization is present in the baboon temporal bone. Since pneumatization is used as a character in phylogenetic analysis, understanding normal patterns of morphological variation and symmetry in temporal bone pneumatization is necessary… [FULL ABSTRACT]

Lawson HA, Hardison R, King D, Martin J, Miller W, and Weiss K.  Examining polymorphism and divergence in non-coding features of craniofacial genes.   The American Journal of Physical Anthropology 132(S44):152. in press

Until the molecular factors underlying primate craniofacial size and shape change are understood, knowledge of hominid skull evolution remains limited. Craniofacial development involves hundreds of genes, organized into networks, creating and shaping the whole in space and time… [FULL ABSTRACT]

Richtsmeier JT, Weiss KM, Buchanan A, Walker A, Jablonski N, Frazier BC, Willmore KE, Lawson H, Yan P, Hill CA, Roseman CC, Cheverud JM, Falk D, Hildebolt CF, and Rogers J.  Developmental genetic basis of primate craniofacial variation and human origins.   The American Journal of Physical Anthropology 132(S44):198. in press

We describe an integrative, collaborative, and multidisciplinary project aimed at understanding the developmental genetic basis of the evolution of craniofacial variation in the genus Homo. We have launched a project that identifies the dimensions of natural craniofacial development, variation and evolution using baboon skulls… [FULL ABSTRACT]

Roseman CC, Willmore KE, Richtsmeier JT, Rogers J, Weiss KM, Walker A, Hildebolt CF, and Cheverud JM.   The genetic basis of phenotypic integration in baboon and mouse craniomandibular morphology with implications for human cranial evolution.   The American Journal of Physical Anthropology 132(S44):202. in press

Here we present results of a quantitative genetic study of cranial morphology in a pedigreed population of baboons and mandibular morphology in the F10 generation of an advanced intercross breeding design in mice… [FULL ABSTRACT]

Willmore KE, Roseman CC, Cheverud JM, Frazier BC, Rogers J, Weiss KM, Walker A, Hildebolt CF, and Richtsmeier JT.   Genetic and phenotypic variation in craniofacial dimorphism in baboons.   The American Journal of Physical Anthropology 132(S44):251. in press

A major determinant of craniofacial form and its evolution is the degree and structure of variation, both at the phenotypic and genetic levels. We hypothesize that differences in variation between sexes are directly related to differences in form… [FULL ABSTRACT]

Funding Agencies
National Science Foundation

Available Data

All of the primary data collected for our project, including the CT scan images of the baboons and mice will be made available to the broader research community upon request. Inquiries regarding the availability of various data sets can be sent to Dr.Joan Richtsmeier.